ESTHESIONEUROBLASTOMA IN A BOY WITH 47, XYY KARYOTYPE

Esthesioneuroblastoma in a boy with 47, XYY karyotype

Neuroblastomas are sometimes associated with abnormal constitutional karyotypes, but the XYY karyotype has been rarely described in neuroblastomas.Here, we report a case of an esthesioneuroblastoma in Stickers a boy with a 47, XYY karyotype.A 6-year-old boy was admitted to our hospital because of nasal obstruction and palpable cervical lymph node,

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Modulation of the Unfolded Protein Response Is the Core of MicroRNA-122-Involved Sensitivity to Chemotherapy in Hepatocellular Carcinoma

The loss of microRNA-122 (miR-122) expression correlates to many characteristic properties of hepatocellular carcinoma (HCC) cells, including clonogenic survival, anchorage-independent growth, migration, invasion, epithelial-mesenchymal transition, and Glass Container tumorigenesis.However, all of these findings do not sufficiently explain the onco

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Analysis of Adverse Reactions in the Assessment of Coronary Microvascular Disease by Adenosine Load and Adenosine Disodium Triphosphate Load

Background The treatment of coronary microvascular disease (CMVD) has always been the focus of non-coronary obstructive ischemic heart disease.Adenosine injection and adenosine disodium triphosphate (ATP) injection, which are common clinical loading drugs to determine coronary flow reserve (CFR) and evaluate CMVD, are related but significantly diff

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Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification

Abstract Background Microarray-based gene expression profiling is a powerful approach for the identification of molecular biomarkers of disease, particularly in human cancers.Utility of this approach to measure responses to therapy is less well established, in part due to challenges in obtaining serial biopsies.Identification of suitable surrogate

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